The Basics of Toxicology for Green Molecular Design

Learn to apply the fundamental principles of molecular toxicology and to use tools that help chemists identify and design safer chemicals. 

Developed and taught in Spring 2012 by Chris Vulpe and Martin Mulvihill.

Green chemistry seeks to promote the adoption of safer more efficient chemicals, products and processes. In order to design inherently safer chemicals it is important to understand the basic principles that dictate toxicity. This 1 unit class will introduce the basic tools and paradigms found in toxicology with a focus on ways to design safer chemicals and processes. 

Learning Goals

  • Understand the basic principles and modes of action that dictate molecular toxicology.
  • Be able to effectively use tools and metrics to evaluate and compare the hazard profile of chemical substances.
  • Understand and identify structure/function relationships with respect to chemical properties, biological activity, and environmental fate.
  • Be able to understand and evaluate the results of common toxicology assays.

Course Materials

Syllabus (PDF, DOC)
Lesson Plans (PDF, DOCX)
Day 1: Lecture - Homework
Day 2: Lecture - Homework
Day 3: Lecture - Homework
Day 4: Lecture - Homework
Day 5: Lecture - Homework
Day 6: Lecture - Homework
Day 7: Lecture - Homework


Creative Commons License

The Basics of Toxicology for Green Molecular Design by Berkeley Center for Green Chemistry is licensed under a Creative Commons Attribution 3.0 Unported License.